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Links to stroke astrazeneca
Cerovive is the registered tradmark of the astrazeneca corporation
for the nxy-059, a derivative of pbn.
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This is of some clinical importance,
since an antiinflammatory pharmaceutical preparation
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rich in SOD
("orgotein") is used in veterinary medicine and recently
has been shown to be both effective and apparently safe in the
treatment of various inflammatory lesions in man.
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active oxygen
species may play a significant role in the etiology of other
inflammatory lesions in man, For example, SOD is reported to be
effective in the treatment of lupus erythematosis,(43,158) and unique
light-activated, superoxide-dependent lymphocyte clastogenic factors
present in the serum of patients with lupus and other collagen
diseases may account for some of the photosensitivity of this group
of disorders.(157-159).
Both direct and indirect production of active
oxygen species may also have a role in the pathophysiology of gout
and other hyperuricemic syndromes.
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Antioxidants such as the methoxyphenols hair loss treatment and
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are apparently effective in the amelioration of both experimental
cerebral edema and spinal cord injury.(17,56). However, once again we
must emphasize that, like most else in this field, the evidence for
free radical involvement in inflammation and neuronal injury is
circumstantial and has not been proven conclusively.
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